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Search Results for " gamma, neuronal "

Targets

4

Compounds

1

Natural Products

7

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T1240 Flumazenil Ro 15-1788 GABA Receptor
Flumazenil (Ro 15-1788) antagonizes the benzodiazepine binding site of the gamma-aminobutyric acid (GABA)/benzodiazepine receptor complex in the central nervous system (CNS), thereby preventing the chloride channel openi...
T6474 Divalproex Sodium Valproate semisodium,Epival HDAC
Divalproex Sodium (Valproate semisodium) binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted by increasing brain concentration of GABA and by inhibiting enzyme...
T28766 SGE-516 SGE516
SGE516 is a neuroactive steroid and a positive allosteric modulator of both gamma- and delta-containing GABAA receptors. SGE516 reduces neuronal firing rates and epileptiform activity in vitro. SGE-516 protects against a...
T76393 Amyloid 17-42
Amyloid 17-42 (Aβ(17-42)), a significant component of diffuse plaques in Alzheimer's disease and cerebellar pre-amyloid in Down's syndrome, results from the alpha- and gamma-secretase cleavage of amyloid precursor protei...
Cat No. Product Name Synonyms Targets
TN3351 Aflatrem GABA Receptor
Aflatrem is a tremorgenic mycotoxin with acute neurotoxic effects, a single low dose of aflatrem is able to induce degeneration of neuronal processes in hippocampal neurotransmitter systems. Aflatrem potentiates the gamm...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-02646 NSE/ENO2 Protein, Human, Recombinant (His) Human E. coli
The combination of silencing ENO2 and 2-deoxyglucose (2-DG) synergistically inhibited leukemia cell survival. ENO2 may be a biological marker for monitoring chemotherapeutic efficacy and relapse in ALL. Reduced ENO2 expr...
TMPY-01355 Transglutaminase 2/TGM2 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
Protein-glutamine gamma-glutamyltransferase 2, also known as Tissue transglutaminase, Transglutaminase C, Transglutaminase-2, and TGM2, is a member of the transglutaminase superfamily. TGM2 plays a role in cell growth an...
TMPH-03037 Alpha-cobratoxin Protein, Naja kaouthia, Recombinant (GST & His & Myc) Naja kaouthia E. coli
Monomer: binds with high affinity to muscular (alpha-1-beta-1-gamma-delta/CHRNA1-CHRNB1-CHRNG-CHRND) nAChR (tested on Torpedo californica, Kd=0.2-4.5 nM) and neuronal alpha-7/CHRNA7 nicotinic acetylcholine receptors (Kd=...
TMPY-04408 CAMKII beta/CAMK2B Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
Calcium/calmodulin-dependent protein kinase II beta (CAMK2B) is a member of the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. CaMKII is an important player in pro...
TMPY-02802 GNG13 Protein, Human, Recombinant (His) Human E. coli
GNG13 is a subunit of heterotrimeric G proteins which consist of alpha, beta, and gamma subunits. Heterotrimeric G proteins are membrane-bound GTPases that are linked to 7-TM receptors. They function as signal transducer...
TMPJ-00281 CADM1 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Cell adhesion molecule 1(CADM1) is a single-pass type I membrane protein and belongs to the nectin family. It contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 Ig-like V-type (immunoglobulin-like) domain. C...
TMPJ-01234 IL-36 gamma Protein, Mouse, Recombinant Mouse E. coli
Interleukin-36 gamma (IL-36γ) is a member of the interleukin 1 cytokine family that includes three closely related genes, IL-36α, β, and γ, formerly known as IL-1F6, F8, and F9 respectively. IL-36α has been detected in b...
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